The San Francisco 49ers entered Saturday's game with just four running backs, and they lost one of them in the third quarter.

The 49ers scored a touchdown on their opening series of the preseason, then their defense crumbled by halftime against the ...

Nearly 40 players are brand new to the 49ers’ roster and poised to make their debut in Saturday’s preseason opener against ...

The San Francisco 49ers added some running back depth to their roster ahead of their preseason opener vs. the Denver Broncos.

The San Francisco 49ers signed running back Ke’Shawn Vaughn to a one-year deal ahead of their first preseason game against the Denver Broncos. Vaughn signed with the 49ers’ practice squad in August ...

The 49ers won't play their starters in their preseason debut against the Denver Broncos, but these 11 players will be worth ...

The key to winning any fantasy football league is identifying sleeper and breakout candidates and getting them on your roster ...

The Radcliff, Ky. native was a wide receiver coming out of North Hardin. LOUISVILLE, Ky. - As fans of the Louisville football program know at this point, the Cardinals have an embarrassment of riches ...

McCaffrey is not in line to play in Saturday's preseason opener against the Broncos, Eric Branch of the San Francisco Chronicle and David Lombardi of SFStandard.com report. With Isaac Guerendo ...

Vaughn will solidify the 49ers' backfield depth with Isaac Guerendo (shoulder) and Jordan James (finger) both sidelined for a few weeks. Vaughn spent most of the 2024 season on the 49ers' practice ...

The 49ers are facing the Broncos in their first preseason game. Here are fiveplayers fans should keep their eyes on during ...