More than one-third of the elevated serum proteins reflected muscle fiber damage and leakage into the bloodstream. A large, reproducible set of blood-based protein biomarkers can reliably distinguish ...

Almost all (97%) of the patients with positive planar imaging and positive single-photon emission computed tomography findings were diagnosed with ATTR-CM. Single-photon emission computed tomography ...

Patients with ATTR-CM who experienced outpatient worsening heart failure had a 2.5-fold increased risk of mortality compared with those who did not. Outpatient worsening heart failure is an ...

The median time to reach a diagnosis of ATTR-CM from the time of heart failure diagnosis was 490 days (1.3 years). There are clinically important delays between the incidence of heart failure and the ...

Patients reported higher habitual levels of physical activity following the PR intervention, shifting from low to moderate activity levels. A 12-month supervised program of pulmonary rehabilitation ...

Data showed berotralstat was well tolerated, maintained a consistent safety profile, and reduced monthly attack rates, with nasopharyngitis being the most commonly reported side effect. Berotralstat, ...

A diagnosis of ATTR-CM in a more recent era was associated with older age, White race, wild‐type disease, and tafamidis treatment. The survival of patients diagnosed with transthyretin-mediated ...

Generalized pustular psoriasis (GPP) is a rare, severe form of psoriasis characterized by the acute onset of eruptions of sterile pus-filled skin lesions and rashes with or without systemic ...