In silico antibody accessibility analysis indicates that ectodomain epitopes are transiently exposed, while MPER epitopes are virtually always occluded in the pre-fusion trimer.
This study presents a comprehensive approach for assessing multiple quality attributes of antibody-oligonucleotide conjugates ...
In an era where scientific accuracy and reproducibility are paramount, the global antibody specificity testing market is ...
Johnson & Johnson’s attempt to develop a $5 billion-a-year Alzheimer’s disease drug has been rocked by a phase 2 flop. A scheduled data review found the anti-tau antibody posdinemab failed to ...
A specially engineered antibody that can infiltrate kidney cysts has shown the ability to block key growth signals driving polycystic kidney disease. Early mouse studies suggest it may halt or even ...
The antibody drug market value is expected to reach $445 billion in the next five years, with over 160 antibodies currently licensed globally for a wide breadth of conditions, including cancer, ...
Creative Commons (CC): This is a Creative Commons license. Attribution (BY): Credit must be given to the creator. Accurate characterization of charge variants in biologics is crucial to uphold ...
B-cell depletion is effective in MS and NMOSD, with anti-CD20 and anti-CD19 mAbs showing distinct mechanisms impacting safety and tolerability. Glycoengineering enhances ADCC activity, mitigating ...
Powerful llama-derived antibodies could be the key to stopping not just current SARS viruses, but future ones too. Scientists have discovered a unique class of nanobodies that clamp the coronavirus ...
Amivantamab is a bispecific antibody targeting epidermal growth factor receptor (EGFR) and mesenchymal-epithelial transition factor, demonstrating efficacy in patients with non–small cell lung cancer ...
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