The calcium-sensing receptor (CaR) was cloned in 1993 from bovine parathyroid gland. 1 Subsequently, the receptor was reported in a wide range of tissues and cell types. It belongs to the superfamily ...

The potential launch of three late-stage pipeline agents will increase the number of pharmacological treatment options. Credit: SewCreamStudio via Shutterstock. The chronic kidney disease ...

Everyone is worried about cholesterol blocking arteries, but not many know that calcium deposits in arteries are also dangerous. Dr Mukesh Goel, senior consultant, cardiothoracic and cardiovascular ...

Calcimimetics suppress the secretion of parathyroid hormone by sensitizing the parathyroid calcium receptor to serum calcium. Cinacalcet (Sensipar ® /Mimpara ®, Amgen Inc., Thousand Oaks, CA), the ...

Japanese drugmaker Kyowa Kirin (TYO: 4151) has received approval in its home country for a higher-dose formulation of its oral calcimimetics agent Orkedia (evocalcet). All the news that moves the ...

Newark, New Castle, USA, June 05, 2023 (GLOBE NEWSWIRE) -- Numerous physiological functions, such as bone health, muscular contraction, neuron function, and blood clotting, depend on calcium ...

Hypercalcemia is a condition in which calcium levels in the blood rises above than normal. This accounts for more than necessary amount of calcium in your blood which can actually weaken your bones.

Primary hyperparathyroidism (PHPT) results in inappropriately excessive secretion of parathyroid hormone (PTH) from the parathyroid gland. High PTH levels trigger various physiological processes to ...

Study findings suggest serum phosphate is a negative modulator of calcium receptor activation. Hyperphosphatemia can diminish the ability of calcimimetics to activate the calcium-sensing receptor, but ...

A recent research report on Global Calcimimetics Market Industry Analysis and Opportunity Assessment 2021-2028 by Data Bridge Market Research comprises of productive information of the market. The ...

Bundled payments are a good idea, until they aren’t—for patients. The idea of paying a combined price rather than piecemeal for a routine medical treatment or procedure has gained traction as a way of ...