A research team led by scientists from the State University of Campinas (UNICAMP) in São Paulo, Brazil, has made significant ...

The epicardium, previously viewed as a passive outer layer around the heart, is now recognized as an essential component in development, regeneration, and repair. In this review, we explore the ...

Pulmonary arterial hypertension (PAH) involves progressive cellular and molecular change within the pulmonary vasculature, leading to increased vascular resistance. Current therapies targeting nitric ...

Mitochondria are essential for cell survival, repair, and adaptation. Not only do they generate most of the energy needed during a cell's life, but they also regulate cell death, calcium balance, and ...

The farnesoid X receptor (FXR) is a nuclear receptor that plays a central role in bile acid regulation, intestinal barrier integrity, immune modulation and microbiome balance, all key factors involved ...

This important study reports an endometrial organoid culture system mimicking the window of implantation. The evidence supporting the conclusion drawn is convincing. The data will be of interest to ...

This study presents a valuable development of endometrial organoid culture methodology that mimics the window of implantation. Functional validation to demonstrate its robustness is lacking; therefore ...

Bone health relies on a balance between osteoblasts (builders) and osteoclasts (recyclers). Peak bone mass occurs in early adulthood; deficiencies during this window amplify fracture risks later in ...

Five years ago, Nobel laureate Carolyn Bertozzi, PhD, and her team described novel small RNA-glycan conjugates, glycosylated RNAs (glycoRNAs), on the cell surface. These small non-coding RNAs have ...

How do immune cells strike a balance, unleashing rapid attacks against pathogens or cancer, while avoiding damage to healthy cells? Research into an immune kill switch holds potential for controlling ...

Abstract: Immunomechanobiology, the study of how physical forces influence the behavior and function of immune cells, is a rapidly growing area of research. It is becoming increasingly recognized that ...

aMedical Clinic 1, Department of Gastroenterology, Ludwig Demling Endoscopy Center of Excellence, University Hospital Erlangen, Friedrich-Alexander University Erlangen-Nürnberg, Erlangen, Germany ...