This valuable study identifies and characterizes probe binding errors in a widely used commercial platform for visualizing gene activity in tissue samples, discovering that at least 21 out of 280 ...
Single cell gene expression studies often rely on single-cell RNA sequencing (scRNA-seq) alone. While scRNA-seq reveals which genes are turned on, it does not capture protein expression or changes to ...
Origin-recognition complex, or ORC, plays an unexpectedly broad role in the regulation of human cell gene expression, according to a study in the journal Cell Reports. This is the first detailed study ...
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Symbiotic bacteria in long-term host ...
Abstract: Spatial transcriptomics (ST), known as an expensive medical examination, plays an important role in analyzing the spatial heterogeneity of tumors. When considering the correlation between ...
A new international study suggests that ancient viral DNA embedded in our genome, which were long dismissed as genetic "junk", may actually play powerful roles in regulating gene expression. Focusing ...
Adeno-associated virus (AAV)–mediated gene therapy has emerged as a promising treatment for hemophilia B. Data on safety and durability from 13 years of follow-up in a cohort of patients who had been ...
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Creative Commons (CC): This is a Creative Commons license. Attribution (BY): Credit must be given to the creator. The gene expression capacity of bacteria depends on the interplay between growth and ...
Traditional meta-analyses pool effect sizes across studies to improve statistical power. Likewise, there is growing interest in joint clustering across datasets to identify disease subtypes for bulk ...
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Mycobacterium tuberculosis causes long-term ...