In summary, macrophages secrete IFN-β, activating the IFN-β-IFNAR-p-STAT1 axis in MICFs, leading to increased secretion of CCL2/7/12 chemokines and subsequent recruitment of more IFN-β-secreting ...

Aging immune cells known as senescent macrophages are emerging as critical players in cancer progression. Rather than defending the body, these aged cells undergo profound functional shifts that ...

This granulomatous reaction may be viewed as a frustrated attempt by the immune system to neutralize antigen. The antigen is trapped within the granuloma and in this location the macrophages secrete ...

While these animals retain the regenerative ability throughout adulthood, most mammals, including mice and humans, lose this capacity shortly after birth. 4 Scientists are interested in determining ...

Randomized, Double-Blind, Controlled Trial of Mitoxantrone/Prednisone and Clodronate Versus Mitoxantrone/Prednisone and Placebo in Patients With Hormone-Refractory ...

Phase III Study of Concurrent Chemoradiotherapy Versus Radiotherapy Alone for Advanced Nasopharyngeal Carcinoma: Positive Effect on Overall and Progression-Free Survival Purpose: We demonstrated that ...