A new mouse study found that unrepaired DNA-protein crosslinks activate inflammatory signaling pathways that trigger early aging disorders.
Researchers have shown that harmful bonds between protein and DNA fuel immune attack in progeria. Pumping up a protein that cuts these bonds could prevent symptoms.
"Hutchinson-Gilford Progeria Syndrome (HGPS) Market"Hutchinson-Gilford Progeria Syndrome Companies include Eiger BioPharmaceuticals, Inc., The Progeria Research Foundation, Ionis Pharmaceuticals, Inc.
A new research paper was published in Volume 17, Issue 9 of Aging-US on August 27, 2025, titled, "Deregulated miR-145 and miR-27b in Hutchinson-Gilford progeria syndrome: implications for adipogenesis ...
“The findings highlight miRNA-145-5p and miRNA-27b-3p as potential therapeutic targets to address adipose tissue defects and premature aging in HGPS” “The findings highlight miRNA-145-5p and miRNA-27b ...
This valuable study analyzes aging-related chromatin changes through the lens of intra-chromosomal gene correlation length, which is a novel computational metric that captures spatial correlations in ...
PEABODY — The Progeria Research Foundation (PRF) will host its 24th annual International Race for Research, a tradition that unites the local community and global supporters in the mission to cure ...
A new breakthrough in a rare genetic disease which causes children to age rapidly has been discovered using 'longevity genes' found in people who live exceptionally long lives—over 100 years old. The ...
Children who develop deep wrinkles, stunted growth, and rapidly aging bones and blood vessels as early as 1 to 2 years of age may be suffering from Hutchinson-Gilford Progeria Syndrome (HGPS), a rare ...
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