Researchers say discoveries could expand the CRISPR toolbox and lead to more efficient, rapid diagnostic tools for detecting COVID-19, influenza, and RSV.

Across all domains of life, immune defenses foil invading viruses by making it impossible for the viruses to replicate. Most ...

A giant impact on the early Earth could have brought the building blocks of RNA to our planet, which new research suggests ...

Not revised: This Reviewed Preprint includes the authors’ original preprint (without revision), an eLife assessment, public reviews, and a provisional response from the authors. The authors have made ...

Every cell depends on proteins to function and stay healthy. These proteins are made inside the cell from amino acids, but cannot simply accumulate inside the cell forever. Once they have done their ...

The role of tRNA as the adaptor in protein synthesis has held an enduring fascination for molecular biologists. Over four decades of study, taking in numerous milestones in molecular biology, led to ...

Collaborative research by the University of Tokyo and RIKEN Center for Biosystems Dynamics Research has led to the development of a new method for simultaneously synthesizing all transfer RNA (tRNA) ...

IntegrateRNA Launches Custom Aminoacyl-tRNA In Vitro Synthesis Service to Advance Protein Engineering IntegrateRNA Launches Custom Aminoacyl-tRNA In Vitro Synthesis Service to Advance Protein ...

Scientists have identified a new class of compounds capable of partially clearing the tropical parasite that causes Chagas disease out of mice, suggesting the molecular group could serve as a source ...

Protein synthesis is a central process in free-living microorganisms and is heavily targeted by antimicrobials. Studies of transfer RNAs (tRNAs), aminoacyl-tRNA synthetases (aaRSs), and ribosomes have ...