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Jan 29, 2025 · Conclusion. Globally, the average age of populations is increasing and the increase in chronic disease is a challenge for health systems. Geroscience research is an emerging field with the potential
Homepage - PHG Foundation
6 days ago · World’s first gene editing therapy now in the UK for sickle cell disease 31st January 2025 For many years, treatment options for sickle cell have been limited, focusing mainly on managing symptoms and preventing complications. The approval by NICE of Exa-cel provides new hope for people living with the disease.
Various forms of gene therapy including CRISPR genome editing, whole gene insertion and expression modification using antisense oligonucleotides are being investigated in many
Whole exome sequencing in clinical genetics - PHG Foundation
PHG Foundation. We are an exempt charity under the Charities Act 2011 and regulated by the Office for Students (OFS) as a connected institution of the University of Cambridge.
Algorithms as medical devices - PHG Foundation
A resource for regulators and policy makers, this report makes recommendations for improving the regulation of digital medical devices
PHG Foundation 6 Interest is growing in how artificial intelligence (AI) or machine learning can be used safely and reliably at scale in routine health care.1 AI and machine learning cover a wide breadth of activities and can simply be defined as a set of complex
Pathogen genomics into practice - PHG Foundation
Genomic technologies have the potential to transform the management of infectious diseases. In Pathogen Genomics Into Practice we set out a roadmap to converting the power of this exciting new technology into services that are high quality, evidence based, and available population-wide on an equitable basis. Pathogen Genomics Into Practice is a comprehensive report into the current state of ...
AI - doing more with less in the NHS - PHG Foundation
6 days ago · From stock market jitters caused by the artificial intelligence (AI) model DeepSeek to Government announcements on the AI Opportunities Action Plan, it can seem that news about AI is everywhere. Research and healthcare are not alone in grappling with how we can make the most of this technology in today’s data heavy world.
Polygenic scores, risk and cardiovascular disease
The potential of polygenic scores to improve risk stratification has reignited enthusiasm around the use of genetic information to help predict and prevent common disease.
Functional genomics Experimentally induced variations Genome editing tools (e.g. CRISPR-Cas) can be used to systematically induce variations in genetic features in high-throughput studies to characterise the