MORE here ⬇️ These are acantholytic keratinocytes ( image from awanui veterinary) A helpful feature of PF ( Pemphigus Foliaceus) is that acantholytic cells are easy to identify on cytology. (When desmosomes that weld keratinocytes together are disrupted, keratinocytes separate from one another, and appear as acantholytic cells on skin cytology) However, acantholysis is not specific to PF! Other diseases—most notably superficial pyoderma (SP) like impetigo—can also produce acantholytic cells and