“It Didn’t Work on Me” #why. Source- https://doi.org/10.1186/s13073-026-01630-0 A recent study published in Genome Medicine reveals that genetic variants in the PAM gene, present in roughly ten percent of the population, can significantly reduce a person's response to GLP-1 medications. The PAM gene produces an enzyme responsible for activating metabolic hormones. Researchers discovered that individuals with these specific variations actually have higher circulating levels of the hormone but exh

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